LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...
Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies. Researchers led by ...
In a TNBC animal model with limited responsiveness to chemotherapy, Telomir-1 demonstrated statistically significant activity ...
There is currently no cure for Alzheimer’s disease, a type of dementia that an estimated 7.2 million Americans age 65 and ...
Every year, more than 100 million animals are used globally in biomedical research, yet over 90% of drugs that appear effective in animal trials fail during human clinical testing. 1 This staggering ...
In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...
A common agricultural pesticide known as chlorpyrifos may play a substantial role in the development of Parkinson’s disease.
Genetically-humanized FcRn mice provide translational pharmacokinetics (PK) and pharmacodynamics (PD) data for antibody-based therapeutics. The image illustrates a therapeutic antibody (blue) adhering ...
One of the biggest quests in biology is understanding how every cell in an animal’s body carries an identical genome yet still gives rise to a kaleidoscope of different cell types and tissues. A ...
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