Most scientists are fortunate if they can make one major discovery in their lifetime. Dr. Paul Zamecnik made two, each of which should have won him a Nobel Prize. Working with Dr. Mahlon Hoagland, he ...

Figure 1: Strategy for the identification of sense-antisense RNA duplexes. To test whether the described method was effective in enriching for endogenous antisense RNA, DNase I–treated total RNA from ...

image: The hypothesis assumes that an entirely new gene is produced from the non-stop frame on the antisense strand of a GC-rich gene after gene duplication, followed by the accumulation of base ...

The FANTOM Consortium for Genome Exploration Research Group, a large international collection of scientists that includes researchers at The Scripps Research Institute's Florida campus, is reporting ...

Most scientists are fortunate if they can make one major discovery in their lifetime. Dr. Paul Zamecnik made two, each of which should have won him a Nobel Prize. Working with Dr. Mahlon Hoagland, he ...

Researchers have devised a molecular structural modification that boosts the efficacy of antisense oligonucleotide-based drugs by replacing the RNA strand of a heteroduplex oligonucleotide with DNA.

In recent years, scientists have found that RNA--once thought to be little more than a bit player in the pathway from gene to protein--stands more center stage, playing a larger and more varied ...

Like the scavengers who rummage for valuable objects in the midst of the leftovers of society, some molecular biologists are extracting precious information from apparently less noble stretches of ...

HAMBURG and MARBURG, GERMANY / ACCESSWIRE / August 5, 2020 / Evotec SE (Frankfurt Stock Exchange: EVT, MDAX/TecDAX, ISIN: DE0005664809) and the leading independent European antisense drug discovery ...

Most scientists are fortunate if they can make one major discovery in their lifetime. Dr. Paul Zamecnik made two, each of which should have won him a Nobel Prize. Working with Dr. Mahlon Hoagland, he ...