Centromeres play virtually the same central role across the entire tree of life: They ensure the faithful segregation of ...
Bacterial chromosome segregation is a fundamental process ensuring accurate distribution of genetic material during cell division. Central to this process is the ParABS system, comprising the ...
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When the number of chromosomes goes off track
The improper segregation of chromosomes during cell division leads to abnormalities that disrupt the proper functioning of the cell. Cells with an abnormal number of chromosomes consequently activate ...
Advancements in genome sequencing have challenged the long-standing belief that the position of the centromere in the chromosome is fixed. Researchers from Okayama University, Japan, have analyzed ...
A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered a new molecular mechanism underlying chromosome alignment during cell ...
DLGAP5 is proposed as a causal gene related to oocyte meiosis disorder for the first time. It expanded the current spectrum of pathogenic genes responsible for the phenotype of oocyte maturation and ...
Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities.
About 50 percent of pregnancies fail, and one of the main reasons is aneuploidy, a genetic condition in which cells do not have the correct number of chromosomes. 1 Aneuploidy commonly arises when ...
During sexual reproduction, haploid gametes (i.e. eggs and sperm) are generated from diploid precursors through the specialized cell division of meiosis. Meiosis reduces ploidy by following one round ...
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