Depression-related fatigue is caused by cellular "overworking" at rest and a failure to produce energy under stress.

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

While modern economic downturns and crises, such as the 2008 financial crisis or recent inflation, have been challenging and created genuine hardship for millions of families, the sheer scale and ...

Here are the long-term impacts of depression and why knowing the signs and symptoms matter for awareness.

ECT can seem like something out of science fiction, but it actually has decades of studies to show how effective it can be in reducing depression symptoms. Depression is one of the most common mental ...

High-functioning depression can impact your quality of life, dampening your enthusiasm for work, school, family, and even ...

Depression remains an ongoing problem in the U.S. as historically high rates persist, polling company Gallup reveals. The reported percentage of U.S. adults suffering or receiving treatment for ...

Depression is a common mental health condition, with symptoms that can range from mild to severe. Around 16% of American adults have struggled with a type of depression at some point during their ...

In the U.S. women are far more likely than men to seek treatment for depression—as with all other conditions. Nevertheless, it is extremely important for anyone suffering to take steps to treat ...