As we age, we don’t recover from injury or illness like we did when we were young. But new research from UC San Francisco has found gene regulators that turn genes on and off that could restore the ...

Senescent fibroblasts are aging cells in connective tissue that no longer divide and protect against tumor development. Yet, these same cells can promote cancer growth in a laboratory setting. Until ...

Peer-reviewed discovery platform and data in PNAS show that single transcription factor modulation reverses aging-associated gene expression and restores healthy cellular and tissue function in models ...

Thus, our studies revealed regulatory mechanisms of glycolysis-driven cellular senescence by AUF1-mediated decay of PGAM1 and PDP2 mRNAs.” "Thus, our studies revealed regulatory mechanisms of ...

Scientists are closing in on a deceptively simple idea with radical implications: that a single protein signal in the blood can push aging immune cells to behave as if they were young again. Instead ...

Aging is often treated as a snapshot: a comparison between young and old, healthy and diseased. But according to the University of California, Riverside (UCR)’s bioengineering professor Joshua Morgan, ...