Integrin α3β1 regulates adhesive interactions of cells with laminins and have a critical role in adhesion-dependent cellular responses. Here, we examined the role of α3β1-integrin in ErbB2-dependent ...

Integrins are heterodimeric transmembrane receptors composed of an α and a β subunit. They mediate cell adhesion to the extracellular matrix and link it to the cellular cytoskeleton and signaling ...

Within the Ig superfamily (IgSF), intercellular adhesion molecules (ICAMs) form a subfamily that binds the leukocyte integrin α Lβ 2. We report a 1.65-Å-resolution crystal structure of the ICAM-3 ...

Thrombospondin is a 420,000-D glycoprotein that has recently been shown to have several properties in common with the members of a class of adhesive proteins. To characterize further the adhesive ...