Tandem mass spectrometry is a powerful tool in proteomics. By ionizing peptides and then fragmenting those ions into smaller product ions, researchers can determine the biomolecules’ amino acid ...

Ions are accumulated in the Zeno trap before being pulsed rapidly into the TOF, meaning up to 20x more fragment ions can be detected. Enabled by a new level of sensitivity, each MS/MS experiment ...

New research published in EPJ D combines mass spectroscopy with a range of other simulation and analytical techniques, allowing researchers to distinguish between two chiral forms of a dipeptide ...

An algorithm designed by researchers from Carnegie Mellon University's Computational Biology Department and St. Petersburg State University in Russia could help scientists identify unknown molecules.

The process of protein identification typically begins with a bottom-up approach, where proteins are enzymatically digested—most commonly with trypsin—into smaller peptides. These peptides are ...

Its true value depends not on the number of detected features but on the reliability of metabolite identification and pathway analysis. Despite well-established guidelines, annotation and definitive ...