By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes ...

Cells working with an expanded genetic code could make more diverse medicines. A new study shows scientists are within striking distance. One of modern biologists' most ambitious goals is to learn how ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...

Synthetic biologists from Yale were able to re-write the genetic code of an organism — a novel genomically recoded organism (GRO) with one stop codon — using a cellular platform that they developed ...

Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein ...

Moving far beyond the capabilities of traditional oligonucleotide synthesis, the advent of advanced synthesis technologies is enabling genetic constructs to be made more rapidly, accurately, ...

DNA is admired for its perfection as a programmable information molecule: it uses repeating polymerization chemistry to link four nucleotide building blocks (adenine, cytosine, guanine, and thymine) ...

Proteins that were present during the origin of life may have consisted of only seven primordial amino acids, a study suggests. The 20 amino acids commonly found in proteins are encoded by a total of ...

Rare diseases, defined by FDA as “a disease or condition that affects less than 200,000 people in the United States” (1), may ...