– License of proprietary RFdiffusion-based model, RFpeptides, provides Vilya with another powerful structure prediction framework for rapid and unique design of potent and selective macrocycles for ...

Snakebite venom remains one of the most neglected global health crises, claiming over 100,000 deaths annually and leaving more than 300,000 survivors with permanent disabilities. However, recent ...

In late 2020, AI pioneer DeepMind achieved a breakthrough 50 years in the making. By predicting the shape of proteins with atomic accuracy, its deep learning algorithm, AlphaFold, all but solved one ...

Proteins are biology’s molecular machines. They’re our bodies’ construction workers—making muscle, bone, and brain; regulators—keeping systems in check; and local internet—responsible for the ...

Researchers at the University of Washington have shown that a generative AI program can help draw up atomically accurate antibodies from scratch—including those capable of binding to bacterial toxins ...

(a) Protein sequence-structure co-design with PocketGen; (b) Dual-layer graph Transformer encoder; (c) Pre-trained protein language model for sequence prediction and efficient fine-tuning. Researchers ...

Deep learning tools for protein design can also be used to create molecules that bind to them. Certain peptides, such as intrinsically disordered proteins (IDPs), are challenging to target due to ...