BOWLING GREEN, KY.- According to the CDC, about 90,000 non-Hispanic Black or African American people in the United States have sickle cell disease. Outside the U.S., the condition is more common in ...

Sickle cell anemia (HbSS) is the homozygous dominant variant and the most common and severe form of the disease. Whereas patients who only inherited one gene encoding for abnormal HbS and a different ...

Recent therapies like hydroxyurea (Droxia, Bristol-Myers Squibb), the first FDA-approved drug for SCD in 1994, increase fetal hemoglobin (HbF), which, through unknown pathways, improves SCD symptoms ...

The Food and Drug Administration has approved the world’s first medicine based on CRISPR gene-editing technology, a groundbreaking treatment for sickle cell disease that delivers a potential cure for ...

Differences in red blood cell stiffness may help to explain variations in the severity of sickle cell disease (SCD), according to a study.

Two experts joined "In Focus" to explain gene editing therapy for sickle cell disease. Cassandra Dobson and Dr. Thomas Moulton explained how CRISPR gene editing works and shared the cost of the ...

Sickle cell anemia causes sickle-shaped cells to block blood flow to the lungs, leading to acute chest syndrome. Common treatment methods involve oxygen supplementation and pain management. Sickle ...

CRISPR gene therapy Casgevy can nearly eliminate sickle cell crises, but difficult stem‑cell collection is delaying access ...

A new breakthrough study led by researchers at the University of Minnesota Twin Cities could explain why patients with the ...

Sickle cell anemia (SCA) is an inherited disorder of red blood cells. Some parents may learn that their infant has this disorder after prenatal testing. Hospitals also test for SCA after birth as part ...

Researchers found higher C-reactive protein levels during the follicular phase in women with sickle cell disease, indicating cycle-linked inflammation shifts.