If you remember back to the Ye Olde times of your probationary period, you might remember the hazardous materials-operations level training segment. In that class, instructors said a whole bunch of ...

Despite the importance of predicting solubility, it is not an easy matter. One approach, using 'brute force' simulations, requires long computing times. Other techniques, while faster, fail to predict ...

High-concentration injectable formulations present unique challenges. Poor solubility issues are often associated with small-molecule APIs formulated for oral administration. Solubility is also ...

Students will be able to plan and carry out an investigation to compare the solubility of different substances, and develop and explain a particle-level model to describe the process of dissolving.

Advanced solutions are improving drug dissolution, absorption, and overall therapeutic performance. Drug solubility directly impacts bioavailability and absorption levels, and thus efficacy and safety ...

Solubility is the property of a solid, liquid, or gaseous chemical substance called solute to dissolve in a solid, liquid, or gaseous solvent to form a homogeneous solution of the solute in the ...

Many, if not most, new active pharmaceutical ingredients have very low aqueous solubility, and this will have a negative impact on their value as potential medicines. This course is designed to ...

IN a recent letter to NATURE, 1 Mr. Nabar and Dr. Desai write: “It is considered that the results obtained from a study of the precipitation of sparingly soluble substances, such as silver chloride, ...

WASHINGTON, D.C., June 6, 2017 -- The solubility of any given substance -- the measure of how well the substance dissolves into another substance referred to as the solvent -- depends on basic ...