JSTOR Daily

Cyclin A Potentiates Maturation-Promoting Factor Activation in the Early Xenopus Embryo via Inhibition of the Tyrosine Kinase That Phosphorylates CDC2

We have produced human cyclin A in Escherichia coli and investigated how it generates H1 kistone kinase activity when added to cyclin-free extracts prepared from parthenogenetically activated Xenopus ...
Nature

Change of venue: fission-yeast cell-division cues actually initiate in the nucleus

In yeast, the CDK and cyclin proteins that drive cell division activate first in the nucleus — a different location in the cell from where was previously thought. James E. Ferrell Jr is in the ...
ascopubs.org

Cyclin E mRNA: Assessing Cyclin-Dependent Kinase (CDK) Activation State to Elucidate Breast Cancer Resistance to CDK4/6 Inhibitors

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated. Relationships are self-held unless noted. I = Immediate Family ...
EurekAlert!

New research paper challenges dogma of cell cycle control

All textbooks describe the cyclin-dependent kinase complex as the one and only/exclusive regulator of the eukaryotic cell cycle. But now University of Groningen scientists have found evidence that a ...
JSTOR Daily

Robust designation of meiotic crossover sites by CDK-2 through phosphorylation of the MutSγ complex

Crossover formation is essential for proper segregation of homologous chromosomes during meiosis. Here, we show that Caenorhabditis elegans cyclin-dependent kinase 2 (CDK-2) partners with cyclin-like ...
ascopubs.org

Effect of cyclin E overexpression on anti-tumor immune responses via activation of the cGAS/STING pathway following radiotherapy.

Evaluating the immune landscape in early onset colorectal cancer patients. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a full text component.