We know the genes, but not their functions—to resolve this long-standing bottleneck in microbial research, a joint research ...

The largest single cell perturbation dataset to-date will be generated and released open source in a new team effort.

Peer-reviewed discovery platform and data in PNAS show that single transcription factor modulation reverses aging-associated gene expression and restores healthy cellular and tissue function in models ...

Machine learning models reveal that histone marks are predictive of gene expression across human cell types and highlight important nuances between natural control and the effects of CRISPR-Cas9-based ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

The SWI/SNF Ig-Fold for Transcription Factor Interactions or 'SWIFT' domain on mSWI/SNF chromatin remodeling complexes engage ...

Noetik, an AI-native biotech company pioneering self-supervised machine learning and high-throughput spatial data to develop ...

This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...

Researchers have uncovered nearly 150 hidden DNA “switches” inside brain support cells that control the activity of genes ...

Abstract: Dementia, a progressive neurodegenerative disorder affecting millions worldwide, poses significant challenges in early diagnosis and targeted treatment due to overlapping clinical symptoms.

Background Previous genome-wide association studies (GWAS) have identified numerous genetic loci associated with juvenile idiopathic arthritis (JIA). However, the functional impact of these ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Autoimmune uveitis (AU) is a group of autoimmune-driven diseases characterized by ...