A shift in the balance between two lipids – cholesterol and sphingomyelin – makes hybrid epithelial-mesenchymal cancer cells less responsive to certain chemotherapy drugs.

Scientists have found that adding a missing phospholipid back into the bloodstream might help improve blood flow and reduce ...

Background Liver metastasis is a major cause of mortality in patients with colorectal cancer (CRC). Understanding how CRC cells influence the formation of hepatic premetastatic niches (PMNs) is ...

NEW ORLEANS — New data from a first-in-human trial of a CRISPR-based gene therapy for cholesterol disorders are giving lipids experts reason for optimism about the approach for treating cardiovascular ...

Peripheral artery disease (PAD), defined by stenosis or occlusion of the extremities (particularly the lower extremities), affects 200 million individuals worldwide, including an estimated 7% of ...

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Let's be honest, we're all drama queens sometimes. Whether you're texting your bestie you're “literally dying” over the latest celebrity gossip or declaring on social media that Monday mornings are ...

Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without laboratory cell manufacturing and ex vivo expansion. The method using targeted ...

Capital investments fund long-term assets crucial for business operations and growth. High capital investment often indicates a robust economy; low investment may signal economic concern. Investors ...

A new material developed at Cornell University could significantly improve the delivery and effectiveness of mRNA vaccines by replacing a commonly used ingredient in lipid nanoparticles (LNPs) that ...

New original research – part of a special JACC focus issue on lipids – adds to the growing body of evidence surrounding lipoprotein(a) (Lp[a]) and its contribution as an independent causal risk factor ...

Obesity and obesity-associated diseases, such as type 2 diabetes mellitus and cardiovascular diseases, have reached pandemic levels worldwide and are major threats to human life. Lipid species within ...