Phenotypic switching of vascular smooth muscle cells (VSMCs) from a contractile to a synthetic state contributes to vascular remodelling in hypertension. While oxidative stress and microRNAs (miRNAs) ...

This study presents valuable findings by demonstrating that specific GPCR subtypes induce distinct extracellular vesicle miRNA signatures, highlighting a potential novel mechanism for intercellular ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. In this manuscript, ...

Introduction: Idiopathic pulmonary fibrosis is a progressive lung disease with a poor prognosis. Alveolar macrophages (AMs) are essential for maintaining lung homeostasis and play a significant role ...

Abstract: Monitoring the levels of biomarkers for diagnostic applications has significant potential for impacts on patient care, but the measurement of all relevant biomarkers for a given set of ...

(Background): Stroke has become a leading cause of mortality and disability worldwide. However, except rehabilitation, there is no effective therapy during chronic phase after ischemic stroke.

Sperm samples are separated into bad and good quality samples in function of their phenotype, but this does not indicate their genetic quality. Here, we used GeneChip miRNA arrays to analyze microRNA ...