Mar 16, 2025 · Direct Compression (DC) is one of the most efficient and widely adopted methods in tablet manufacturing due to its simplicity and minimal processing steps. However, its …

Mar 12, 2024 · Today, the term direct compression (or direct compaction) is used to define the process by which tablets are compressed directly from powdered active drug substance and …

Jun 12, 2025 · Developing oral tablets containing low-dose actives in the range of 1 to 10 milligrams is often most efficient through the direct compression route. Compared to wet …

Apr 1, 2019 · Direct compression (DC) is the easiest and most cost-effective process for tablet manufacturing, because it only involves blending and compression.

Among the most common techniques for tablet manufacturing are direct compression, dry granulation, and wet granulation. Direct compression (DC) is a highly efficient method for …

Direct compression (DC) requires blending, mixing, and compression of the ingredients into tablets without going through the wet granulation process that requires milling, drying, …

Apr 14, 2025 · For a direct compression (DC)-based formulation to succeed, it demands strategic selection of excipients, API characterization, and continuous optimization based on product …

Direct compression offers a faster, more efficient method for tablet manufacturing by eliminating granulation, drying, and milling steps. The article explores how success with this process …

With direct compression, tablet manufacture can be carried out without the involvement of moisture and heat. Hence, product stability is almost always ensured.

Oct 10, 2019 · Compressed tablets can be made using a wet-granulation process followed by compression or simply by direct compression (DC). DC tableting has been steadily increasing …