Jul 25, 2025 · Michael T Modic (fl. 2024) is an American neuroradiologist at the Vanderbilt University Medical Center in Nashville, Tennessee, in the US, although almost the whole of his career prior to …

Aug 10, 2025 · Modic changes represent an important finding on spine MRI scans that can help explain chronic back pain and guide treatment decisions. While these changes indicate bone marrow …

Modic changes represent a dynamic endplate–marrow process that co-evolves with disc degeneration and can play a significant role in vertebrogenic back pain. For clinicians, the extent of the …

Modic changes are pathological changes in the bones of the spine, the vertebrae. These changes are situated in both the body of the vertebrae and in the end plate of the neighboring disc.

Aug 21, 2025 · Modic changes are categorized into three main types, each reflecting different biological processes within the vertebral bone marrow and appearing distinctly on MRI. These types are …

Modic changes (MC) are a dynamic phenomenon and their etiology is still in debate. Disc/end plate injury, occult discitis and autoimmune reactions appear to set off an inflammatory cascade, leading to …

Jul 4, 2023 · Modic changes refer to specific patterns of abnormalities observed in the vertebral bone marrow of the spine. These changes are typically identified through magnetic resonance imaging …

May 10, 2025 · Modic changes refer to some abnormal signal on the bone marrow of the vertebrae adjacent to a spinal disc. They look like abnormal coloring on the top and bottom of the vertebrae.

Jun 16, 2023 · In less than 5 minutes, you’ll better understand Modic classifications, causes, treatment options, and the truth about the relationship between Modic changes and pain.

In this paper, we review the literature relevant to this topic and discuss the currently available evidence regarding the pathologic and clinical significance of Modic changes.