A. Explain why an inherited deficiency in complement components C 3 or C 4 can result in less efficient clearance of immune complexes from the blood and lymph than normal. B. What clinical symptoms can this lead to? C. What is the only known effect of deficiencies in complement components C5-C9? Explain this effect. | Numerade
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What is complement deficiency? Complement deficiencies are a group of disorders, all of which have a deficiency in one or more complement proteins. Overall, the complement system helps with three important processes: inflammation, phagocytosis, and the creation of membrane attack complexes. Typically, complement deficiencies lead to recurrent bouts of infection or autoimmune reactions. To learn more, check out our video: http://osms.it/compl2f485 #Osmosis #learnmedicine #hematology | Osmosis fro
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Complement C3 - targeted intervention as a novel host modulation therapy in periodontal diseases Gingivitis and periodontitis are prevalent inflammatory diseases of the periodontal tissues. Current treatments are often ineffective or do not prevent disease recurrence. Uncontrolled complement activation and resulting chronic gingival inflammation is a hallmark of periodontal diseases. We have developed a novel safe and efficacious treatment by using the complement 3-targeted therapeutic, AMY-101,
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